Abraham B. Korol, Professor of Genetics 

Institute of Evolution, University of Haifa
Tel: (972)-48240-449; Fax: (972)-48246-554
E-mail: korol@research.haifa.ac.il		   



Education and Degrees
1991 - Rank of 'Full Professor' of Genetics (awarded by the Presidium of USSR Academy of Science).
1988 - Doctor of Biological Sciences (in Genetics), Department of Biology, Leningrad State University.
1976 - PhD, Institute of General Genetics, USSR Academy of Science (Moscow).
1971 - M.Sc. in Computer Science, Leningrad Technical University.

Experience and Positions
since 1997 - Professor of Genetics, University of Haifa
since 1991 - Head, Laboratory of Mathematical & Population Genetics and Laboratory of Drosophila Genetics, Institute of Evolution, University of Haifa
1989 - 1991 Head, Laboratory of Population Genetics, Institute of Ecological Genetics, Moldavian Academy of Science, Kishinev (USSR).
1985 - 1977 Head Laboratory of Genetic Control of Recombination, the same Institute.
1982 - 1990 Associated Professor, Department of Biology, Kishinev State.

University (simultaneously)

Research Interests
- Genetic control and evolution of recombination in higher organisms.
- Molecular-genetic basis of adaptation to stressful and fluctuating environments.
- Genome organization, sequence comparisons on the above-gene level.
- Genetic architecture of complex traits, genetic mapping, including QTL mapping (http://www.multiqtl.com).

- Model organisms: Drosophila, plants, mammals & humans, fungi.

 

Publications: Four books and about 200 papers on population genetics, evolution, plant and Drosophila genetics; recombination phenomenology and genetic mapping.

Zhuchenko A.A. & Korol A.B. 1985. Recombination in Evolution and Selection. Moscow, Nauka Publ., 400 pp. (in Russian).

Zhuchenko A.A., Korol A.B. & Gorodetsky V.P. 1988. Experimental modeling of recombination microevolution. Doklady Academii Nauk USSR 302: 452-456 (in Russian).

Korol A.B. & Preygel I.A. 1989. Increase of recombination in multilocus system under environmental fluctuations. Genetika 25: 923-931 (in Russian). [English translation in Soviet Genetics 1989, 25: 619-626 (Plenum Publ. Co., N.Y)].

Vizir I.Yu. & Korol A.B. 1990. Sex difference in recombination frequency in Arabidopsis. Heredity 65: 379-383.

Preygel S.I. & Korol A.B. 1990. Evolution of recombination in systems of "host-parasite" type. Multilocus models. Genetika 26: 349-58 (in Russian) [English translation in Soviet Genetics 1990, 26: 218-226 (Plenum Publ. Co., N.Y.)].

Korol, A.B., Preygel, I.A. & Preygel, S.I. 1994. Recombination Variability and Evolution. (Chapman & Hall, London).

Korol A.B. & Iliadi K.G. 1994. Recombination increase resulting from directional selection for geotaxis in Drosophila. Heredity 72: 64-68.

Korol A.B., Ronin Y.I. & Kirzhner V.M. 1995. Interval mapping of quantitative trait loci employing correlated trait complexes. Genetics 140: 1137-1147.

Kirzhner, V.M., Korol, A.B., & Nevo, E.1996. Complex dynamics of multilocus systems subjected to cyclical selection. Proc. Nat. Acad. Sci. USA 93: 6532-6535.

Korol A., Kirzhner V., Ronin Y. & Nevo, E. 1996. Cyclical environmental changes as factor maintaining genetic polymorphism. II. Two-locus diploid selection. Evolution 50: 1432-1441.

Nevo E., Rashkovetsky E., Pavliceck T. & Korol A. 1998. A complex syndrome in Drosophila caused by adaptation to microsite contrasts. Heredity 80: 9-16.

Korol A.B., Ronin Y.I. & Nevo E. 1998. Approximated analysis of QTL-environmental interaction with no limits on the number of environments. Genetics 148: 2015-1028.

Korol A., Kirzhner V.M. & Nevo, E. 1998. Dynamics of recombination modifiers caused by cyclical selection: Interaction of forced and auto-oscillations. Genetical Research 72: 135-148.

Korol A.B. 1999. Selection for adaptive traits as a factor of recombination evolution: Evidence from natural and experimental populations (a review). In: S.P. Wasser (ed.), Evolutionary Theory and Processes: Modern Perspectives. Kluwer Academic Publishers, pp. 31-53.

Ronin Y., Korol A. & Nevo E. 1999. Single-and multiple-trait analysis of linked QTLs: some asymptotic analytical approximation. Genetics 151: 387-396

Kirzhner V., Korol A.B. & Nevo E. 1999. Abundant multilocus polymorphisms caused by genetic interaction between species on the trait-for-trait basis. Jour. Theor. Biol. 198: 61-70.

Korol, A.B., E. Rashkovetsky, K. Iliadi, P. Michalak, Y. Ronin & E. Nevo. 2000. Non-random mating in Drosophila melanogaster laboratory populations derived from closely adjacent ecologically contrasting slopes at the "Evolution Canyon", Israel. Proc. Natl. Acad. Sci. 97: 12637-12642.

Peng J.H., A. B. Korol, T. Fahima, M. S. Rцder, Y. I. Ronin, Y. C. Li, & E. Nevo, 2000. Molecular genetic maps in wild emmer wheat, Triticum dicoccoides: genome-wide coverage, massive negative interference, and putative quasi-linkage. Genome Research 10:1509-1531.

Korol A., Y. Ronin, A Itzcovich & E.. Nevo. 2001. Enhanced efficiency of QTL mapping analysis based on multivariate complexes of quantitative traits. Genetics 157:1789-1803.

Korol A.B. 2001. Recombination. In: Encyclopedia of Biodiversity. V.5. Academic Press, San Diego, pp. 53-71.

Nevo E., Korol, A.B., Beiles, A. & Fahima T. 2002. Evolution of Wild Emmer Wheat: Population genetics, genetic resources, and genome organization of wheat's progenitor, Triticum dicoccoides. Springer-Verlag.

Michalak, P., Minkov, I., Helin, A., Lerman, D.N., Bettencourt, B., Feder, M., Korol, A. & Nevo, E. 2001. Genetic evidence for adaptation-driven incipient speciation of Drosophila melanogaster along a microclimatic contrast in "Evolution Canyon", Israel. Proc. Natl. Acad. Sci. USA 98:13195-13200.

Ryndina, A., Kirzhner, V., Nevo E. and A. Korol. 2001. Polymorphism maintenance in populations with mixed random mating and apomixis subjected to stabilizing and cyclical selection. J. Theor. Biol. 212:169-181.

Iliadi, K., Iliadi, N., Rashkovetsky, E., Minkov, I. Nevo, E., Korol, A. 2001. Sexual and reproductive behavior of Drosophila melanogaster from a microclimatically interslope differentiated population of "Evolution Canyon" (Mt Carmel, Israel). Proc. Roy. Soc. London Ser. B 268: 1-10.

Li, Y., Korol, A.B. Fahima, T., Beiles A., Nevo, E. 2002. Microsatellites: Genomic distribution, putative functions, and mutational mechanisms (a review). Molec. Ecol. 11: 2543-2565.

Kirzhner, V.M, A.B. Korol, A. Bolshoy and E, Nevo. 2002. Compositional spectrum revealing patterns for genomic sequence characterization and comparison. Physica A 312: 447-457.

Grishkan, I.B., Korol, A.B., Wasser, S.P., Nevo, E. 2003. Stress and sex evolution in soil microfungi. Proc. Roy. Soc. B 270: 13-18.

Peng, J., Ronin, Y., Fahima, T., Rцder, M.S., Li, Y., Nevo, E. Korol, A.B. 2003. Domestication quantitative trait loci in Triticum dicoccoides, the progenitor of wheat. Proc. Natl. Acad. Sci. USA 100: 2489–2494.

Ronin, Y, Korol, A., Shtemberg, M., Nevo, E., Soller, M. 2003. High resolution mapping of quantitative trait loci by selective recombinant genotyping. Genetics 164: 1657-1666.

Mester, D.I. Ronin, Y.I., Hu, Y, Nevo, E., Korol, A. 2003. Efficient multipoint mapping: Making use of dominant repulsion-phase markers. Theor. Appl. Genet. 107: 1102-1112.

Mester D., Ronin Y., Minkov D., Nevo E., Korol A. 2003. Constructing large scale genetic maps using evolutionary strategy algorithm. Genetics 165: 2269-2282.

Paz, A., D. Mester, I. Baca, E. Nevo, A. Korol, 2004. Adaptive role of increased frequency of polypurine tracks in mRNA sequences of thermophilic prokaryotes. Proc. Natl. Acad. Sci. USA 101: 2951-2956.

Kirzhner V.M., Frenkel V.M., Korol A.B. 2004. Complex dynamics of multilocus genetic systems caused by cyclical selection. In: S.P. Wasser (ed.), Evolutionary Theory and Processes: Modern Horisons. Kluwer Academic Publishers, pp. 65-108.

Li, Y., Korol, A.B., Fahima, T., Beiles A., Nevo, E. 2004. Microsatellites within genes: Structure, function, and evolution. Mol. Biol. Evol. 21: 991-1007.

Suprunova T., T. Krugman, T. Fahima, G. Chen, I. Shams, A. Korol and E. Nevo. 2004. Differential expression of dehydrin genes in wild barley Hordeum spontaneum, associated with resistance to water deficit. Plant Cell Env. 27: 1297-1308.

Lupu A Rashkovetsky E, Nevo E, Korol A. 2004. DNA repair efficiency and thermotolerance in Drosophila melanogaster from "Evolution Canyon". Mutagenesis 19: 383-390.

Mester D., Ronin Y., Nevo E., Korol A. 2004. Fast and high precision algorithms for optimization in large-scale genomic problems. Comp. Biol. & Chem. 28: 281–290.

Zamorzaeva I.,, E. Rashkovetsky, E. Nevo, A. Korol. 2005. Sequence polymorphism of candidate behavioral genes in Drosophila melanogaster flies from "Evolution Canyon". Molecular Ecology (in press).