CV Anatolii Mamchur
Dr. Anatolii Mamchur
Date of birth: May 4, 1984
Place of Birth: Donetsk district, Ukraine
2001 – 2006 Donetsk National University, Faculty of Biology
2006 – 2010 Ph.D. student in Cancer Biology, R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, Kyiv
Thesis title: Anti-VEGF and hematoporphyrin conjugate as the mean to enhance the efficiency of photodynamic cancer therapy
Supervisor: Dr. Lisniak I.O.
Brief synopsis of research: The dissertation is devoted to the study of the photodynamic cancer therapy (PDT) efficiency while using photosensitizes (hematoporphyrin) conjugated with antibodies to VEGF. The conjugate of hematoporphyrin and antibodies to VEGF was received by the method of conjugation with the help of linker carbodiimide-HCl; spectral characteristics of conjugate, its phototoxicity, specific activity in antigen-antibody reactions, character of accumulation in the zones of active vessels formation.
2010 – 2011 PhD, Staff Researcher , Department of Radiobiology and Ecology (Laboratory of quantum nanobiology), R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, Kyiv (www.onconet.kiev.ua)
I worked in the field of photodynamic cancer therapy. My work involved the study of the target photodynamic cancer therapy (PDT) efficiency while using photosensitizer (chlorine) with colloidal gold nanoparticles.
2012 – 2014 PhD, Staff Researcher, Department of Cell and Tissue Technologies (Laboratory of Cell and Tissue Cultures), State Institute of Genetic and Regenerative Medicine (www.igrm.kiev.ua ).
I worked in the field of bone marrow mesenchymal stem cells cultivation, adipose derived stem cells cultivation and research of directed differentiation these cells, use mesenchymal stem cells in the treatment of different injuries (models of inducting ischemic lesion, burn wound)
Research interests. : Cancer resistance in the subterranean mole-rats Spalax: the role of Spalax bone marrow derived mesenchymal stem cells and adipose derived stem cells in tumor growth and angiogenesis